Lot-to-lot variability of antibiotic medium 3 used for testing susceptibility of Candida isolates to amphotericin B

Collaborative study of antibiotic medium 3 and flow cytometry for identification of amphotericin B-resistant Candida isolates.

Center 1 used the National Committee for Clinical Laboratory Standards M27-A2 method and antibiotic medium 3 (AM3) test to determine amphotericin B resistance in 5 of 30 Candida isolates. These isolates were tested at center 2 by AM3 test and flow cytometry (FC). The agreements (C1-C2) were 90% for AM3 test and FC and 73% for the AM3 tests.

Susceptibility of Candida isolates to Amphotericin B and Imidazole: effect of CCCP on Imidazole activity

Nine Candida strains (one C. dublinienses , six Candida albicans, two C. tropicalis, and one C. krusei ) isolated from human genital specimens were characterized based on their susceptibility to amphotericin B and imidazole (done by an adaptation of the National Clinical Laboratory Standards Broth Macrodilution method). All the nine strains were susceptible to amphotericin B with minimum inhibi...

How to Use MRP in Continuous Production Industries When Order Type is Lot for Lot

The Materials Requirements Planning (MRP) method that is applied in production planning and management has some weaknesses. One of its weaknesses is that the time in MRP method is discrete, and is considered as time period. Hence we are not able to order our requirements at irregular time moments or periods. In this paper, a new form of MRP is introduced that is named Continuous Materials Requi...

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Survey of amphotericin B susceptibility of Candida clinical isolates determined by Etest.

BACKGROUND AND PURPOSE The minimal inhibitory concentrations (MICs) of amphotericin B (AmB) determined by the National Committee for Clinical Laboratory Standards (NCCLS; NCCLS document M27-A) broth dilution method are in a relatively narrow ranges and this may lead to underestimation of the AmB-resistant rate in clinical isolates. We evaluated in vitro susceptibility of clinical isolates of Ca...